An unknown number of people have died after a powerful tornado ripped through a small town in Iowa.

Dramatic pictures showed the destruction left behind in Greenfield, with police confirming there had been fatalities and at least a dozen injuries, without being able to provide specific figures.

The devastation came as multiple tornadoes rolled through the US Midwest.

At least three 250-foot-high wind turbines were toppled by an apparent tornado in southwest Iowa.

One turbine was in flames, with black smoke pouring from the bent structure.

Officials said most of Greenfield, with a population of about 2,000 people, had been destroyed, with rescue efforts continuing in an attempt to find survivors.

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A trail of destruction was left behind in Greenfield. Pic: AP

Damage is seen after a tornado moved through Greenfield, Iowa, Tuesday, May 21, 2024. (AP Photo/Hannah Fingerhut)
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Pic: AP

A firefighter walks among tornado-damaged homes, Tuesday, May 21, 2024, in Greenfield, Iowa. (AP Photo/Charlie Neibergall)
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Pic: AP

Pic: AP A damaged car sits on a street after a tornado Tuesday, May 21, 2024, in Greenfield, Iowa. (AP Photo/Charlie Neibergall)
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Pic: AP

Buildings, including homes and businesses, were flattened, trees shredded, and vehicles thrown down the streets which were left strewn with piles of debris.

Sgt Alex Dinkla, a spokesperson for the Iowa State Patrol, said: “This tornado has devastated a good portion of this town.

“Sadly, we can confirm that there have been fatalities. We’re still counting at this time.”

Pic: AP The remains of a tornado-damaged wind turbine touch the ground in a field, Tuesday, May 21, 2024, near Prescott, Iowa. (AP Photo/Charlie Neibergall)
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The extreme conditions in Iowa brought down wind turbines. Pic: AP

The remains of a tornado-damaged wind turbine touch the ground in a field, Tuesday, May 21, 2024, near Prescott, Iowa. (AP Photo/Charlie Neibergall)
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Pic: AP

Pic: AP The remains of a tornado-damaged wind turbine touch the ground in a field, Tuesday, May 21, 2024, near Prescott, Iowa. (AP Photo/Charlie Neibergall)
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Pic: AP

He said Greenfield’s hospital was among the buildings that were damaged, which meant at least a dozen people who were hurt had to be taken to facilities elsewhere.

Residents helped each other salvage their belongings as they tried to come to terms with what had happened.

Pic: AP A firefighter walks among homes destroyed by a tornado Tuesday, May 21, 2024, in Greenfield, Iowa. (AP Photo/Charlie Neibergall)
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Pic: AP

Workers search through the remains of tornado-damaged property, Tuesday, May 21, 2024, in Greenfield, Iowa. (AP Photo/Charlie Neibergall)
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Pic: AP

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Rogue Paxton said he sheltered in the basement of his home when the storm moved through.

He told WOI-TV he thought his family was lucky not to lose their house.

“But everyone else is not so much, like my brother Cody, his house just got wiped,” he said.

“Then you see all these people out here helping each other.

“Everything’s going to be fine because we have each other, but it’s just going to be really, really rough. It is a mess.”

The storms followed days of extreme weather which has ravaged much of the middle section of the US.

Strong winds, large hail and tornadoes swept across parts of Oklahoma and Kansas late Sunday, damaging homes and injuring two people.