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A two-time All-Star, Mikolas is 54-53 with a 3.93 ERA in 178 career games (150 starts) with the San Diego Padres (2012 to ’13), Texas Rangers (2014) and Cardinals. He began playing with St. Louis in 2018 after pitching for the Yomiuri Giants of Nippon Professional Baseball in Japan from 2015 to ’17.
Gray, 34, was removed from a start earlier this month due to tightness in his right hamstring.
The Cardinals signed Gray to a three-year, $75 million deal in free agency, part of a remake of their pitching staff that included adding Lance Lynn and Kyle Gibson.
Last season with the Minnesota Twins, Gray finished second in Cy Young Award balloting with an 8-8 record and 2.79 ERA in 32 starts.