Boston College‘s offensive line, one of the most snakebit position groups in college football, is enduring another setback.

Starting left guard Finn Dirstine has been ruled out against Louisville on Saturday with an upper-body injury. Boston College will be down three players who were expected starters on the offensive line this summer. A fourth starter, left tackle Ozzy Trapilo, will be limited for a second straight game.

This means Boston College will start a pair of players at guard — redshirt junior Jackson Ness at left guard and redshirt sophomore Dwayne Allick at defensive line — who have spent time at defensive line in their BC careers.

Trapilo played 27 snaps at left tackle against Florida State last week, and a source indicated he’s going to attempt to play more as he is battling a leg injury. Nick Thomas, a former preferred walk-on, will spell Trapilo at left tackle.

The Eagles offensive line suffered a huge blow heading into camp when All-ACC guard and top NFL draft prospect Christian Mahogany tore an ACL. Starting right tackle Kevin Cline tore an ACL in September.

That has left Boston College struggling to find any cohesion on the offensive line, as the team ranks 128th in rushing offense and 121st in total offense.

The Eagles are 1-3 and in search of their first ACC win against Louisville (noon, ACC Network) on Saturday.