U.S. Open champion Emma Raducanu was knocked out of the Upper Austria Ladies Linz after a 6-1, 6-7 (0), 7-5 defeat to Chinese qualifier Xinyu Wang on Tuesday.

The 18-year-old Briton, who was the top seed at a WTA event for the first time, held serve in the opening game but lost the next six, while winning just two points on 106th-ranked Wang’s serve.

Raducanu lost a 4-2 lead in the second set but won it in the tiebreaker. She took a medical timeout before saving two match points on Wang’s serve at 5-4 in the third but the qualifier broke Raducanu again and closed out the win in her next service game.

Wang next plays Alison Riske, who defeated eighth-seeded American Alizé Cornet 6-4, 6-4.

Second-seeded Simona Halep reached the quarterfinal after beating Aliaksandra Sasnovich of Belarus 7-5, 6-3, and third-seeded Danielle Collins of the United States eased past Greet Minnen of Belgium 6-1, 6-2.

Alison Van Uytvanck of Belgium, Jaqueline Cristian of Romania, and Jasmine Paolini of Italy also advanced.